'p-BMAL1:p-CLOCK/NPAS2:DNA [nucleoplasm]' positively regulates 'Expression of NOCTURNIN' ACTIVATION Pubmed18587630 Reactome Database ID Release 43549581 Reactome, http://www.reactome.org ReactomeREACT_27087 The phosphorylated BMAL1:CLOCK heterodimer binds an E-box element in the promoter of the NOCTURNIN gene and activates transcription of NOCTURNIN. NPAS2 is predicted to act redundantly with CLOCK. Expression of NOCTURNIN p-BMAL1:p-CLOCK/NPAS2:DNA