'p-BMAL1:p-CLOCK/NPAS2:DNA [nucleoplasm]' regulates 'Expression of DEC2 (BHLHE41, BHLHB3)' As inferred from mouse, the BMAL1:CLOCK heterodimer binds E-box elements in the promoter of the DEC2 (BHLHE41, BHLHB3) gene and activates transcription of DEC2. Reactome Database ID Release 43879843 Reactome, http://www.reactome.org ReactomeREACT_27123 Expression of DEC2 (BHLHE41, BHLHB3) p-BMAL1:p-CLOCK/NPAS2:DNA