dIDP + H2O => dIMP + Pi Authored: D'Eustachio, P, 2012-10-05 Edited: D'Eustachio, P, 2012-10-05 NUDT16 dimer catalyzes the reaction of dIDP and water to form dIMP and Pi (orthophosphate). Mg++ is required for enzymatic activity. The protein is mostly located in the nucleus and concentrated in the nucleolus, where it can also mediate the decapping of U8 small nucleolar RNA (Iyama et al. 2010; Peculis et al. 2007). NUDT16 hydrolyses dIDP to dIMP Pubmed17567574 Pubmed20385596 Reactome Database ID Release 432509793 Reactome, http://www.reactome.org ReactomeREACT_150234 Reviewed: Ito, Riyoko, 2012-10-05