IDP + H2O => IMP + Pi Authored: D'Eustachio, P, 2012-10-05 Edited: D'Eustachio, P, 2012-10-05 NUDT16 dimer catalyzes the reaction of IDP and water to form IMP and Pi (orthophosphate). Mg++ is required for enzymatic activity. The protein is mostly located in the nucleus and concentrated in the nucleolus, where it can also mediate the decapping of U8 small nucleolar RNA (Iyama et al. 2010; Peculis et al. 2007). NUDT16 hydrolyses IDP to IMP Pubmed17567574 Pubmed20385596 Reactome Database ID Release 432509816 Reactome, http://www.reactome.org ReactomeREACT_150396 Reviewed: Ito, Riyoko, 2012-10-05