Phosphopantothenoylcysteine is decarboxylated Authored: Jassal, B, 2007-04-24 08:38:46 EC Number: 4.1.1.36 Pubmed11923312 Pubmed15581364 Reactome Database ID Release 43196840 Reactome, http://www.reactome.org ReactomeREACT_11231 The decarboxylation of phosphopantothenoylcysteine is carried out by phosphopantothenoylcysteine decarboxylase (PPCDC). PPCDC is cytosolic and exists as a homotrimer, binding one FMN cofactor per subunit. While a second isoform has been inferred from large-scale sequnceing studies, it lacks the protein's FMN-binding domain and would thus appear to be nonfunctional if it is expressed.