Cytosolic folate export across the plasma membrane Pubmed17129779 Pubmed8662720 Reactome Database ID Release 43200646 Reactome, http://www.reactome.org ReactomeREACT_11104 SLC46A1 protein in the plasma membrane mediates the reversible transport of folate between the extracellular space and the cytosol. Retention of folate within the cell is dependent on polyglutamate addition (Qiu et al. 2006; Chen et al. 1996).