(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine Authored: D'Eustachio, P, 2010-07-07 EC Number: 2.6.1.40 Edited: D'Eustachio, P, 2010-07-07 Mitochondrial AGXT2 tetramer catalyzes the reaction of (R)-3-aminoisobutyric acid and pyruvate to form 2-methyl-3-oxopropanoate and alanine. While the human mitochondrial AGXT2 enzyme has been characterized experimentally in other respects (Rodionov et al. 2010), its ability to catalyze this transamination reaction is inferred from the properties of its rat homologue. Pubmed20018850 Reactome Database ID Release 43909780 Reactome, http://www.reactome.org ReactomeREACT_25332 Reviewed: Jassal, B, 2010-11-09