XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate Authored: D'Eustachio, P, 2004-02-23 15:33:00 Cytosolic GMP synthase (GMPS) catalyzes the reaction of xanthosine 5'-monophosphate (XMP), ATP, glutamine and water to form guanosine 5'-monophosphate (GMP), AMP, glutamate and pyrophosphate. GMPS is a monomer (Hirst et al. 1994; Nakamura and Lou 1995). EC Number: 6.3.4.1 Edited: D'Eustachio, P, Jassal, B, 0000-00-00 00:00:00 Pubmed7706277 Pubmed8089153 Reactome Database ID Release 4373792 Reactome, http://www.reactome.org ReactomeREACT_628 xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate