15S-HpETE is reduced to 15S-HETE by GPX1/2/4 Authored: Williams, MG, 2012-02-24 EC Number: 1.11.1.9 Edited: Williams, MG, 2012-02-24 Glutathione peroxidases (GPXs) in human platelets (either GPX1, GPX2, or GPX4 are present in the cytosol) are involved in reducing 15S-hydroperoxyeicosatetraenoic acid (15S-HpETE) to 15S-hydroxyeicosatetraenoic acid (15S-HETE) (Hill et al. 1989). Pubmed2501828 Reactome Database ID Release 432161791 Reactome, http://www.reactome.org ReactomeREACT_150230 Reviewed: Rush, MG, 2012-11-10 has a Stoichiometric coefficient of 2