TrXA3/B3 HXA3/B3 HXA3/B3 is hydrolysed to TrXA3/B3 by HXEH Authored: Williams, MG, 2012-02-24 EC Number: 3.3.2.7 Edited: Williams, MG, 2012-02-24 Pubmed2722835 Pubmed6406490 Pubmed8829479 Pubmed9540966 Reactome Database ID Release 432161949 Reactome, http://www.reactome.org ReactomeREACT_150426 Reviewed: Rush, MG, 2012-11-10 The epoxy moiety of hepoxilin A3 (HXA3) and B3 (HXB3) is labile and can be hydrolysed either by a hepoxilin specific epoxide hydrolase (HXEH) or in acidic aqueous solution to form the corresponding diol metabolites trioxilin A3 (TrXA3) and B3 (TrXB3) (Anton et al. 1995, Anton et al. 1998, Pace-Asciak et al. 1983, Pace-Asciak & Lee 1989).