EET(1) DHET(1) EET(1) is hydrolysed to DHET(1) by EPHX2 Authored: Williams, MG, 2012-02-24 EC Number: 3.3.2.10 Edited: Williams, MG, 2012-02-24 Epoxide hydrolase 2 (EPHX2) hydrolyses 5,6-, 8,9-, 11,12-, and 14,15-epoxyeicosatrienoic acids ("EET(1)") to their corresponding dihydroxyeicosatrienoic acids ("DHET(1)") (Werner et al. 2002; Gomez et al. 2004). The majority of the EET biological activities are diminished by this hydrolysis. Pubmed12468260 Pubmed15096040 Reactome Database ID Release 432161961 Reactome, http://www.reactome.org ReactomeREACT_150274 Reviewed: Rush, MG, 2012-11-10