Arachidonic acid is epoxidated to 5,6-EET by CYP(4) Authored: Williams, MG, 2012-02-24 Edited: Williams, MG, 2012-02-24 Pubmed15258110 Pubmed8631948 Reactome Database ID Release 432161890 Reactome, http://www.reactome.org ReactomeREACT_150442 Reviewed: Rush, MG, 2012-11-10 Several cytochrome P450s (CYPs) convert arachidonic acid to 5,6-epoxyeicosatrienoic acid (5,6-EET). The CYPs and their references are as follows: CYP1A1, CYP1A2, CYP1B1 (Choudhary et al. 2004); CYP2J2 (Wu et al. 1996).