Galactocerebrosidase cleaves the galactosyl bond of galactocerebroside to form ceramide Authored: Jassal, B, 2011-09-23 EC Number: 3.2.1.46 Edited: Jassal, B, 2011-09-23 Galactocerebrosidase (GALC) hydrolyses the galactosyl moiety from galactocerebroside (also called galactosylceramide, GalCer) to form ceramide (Sakai et al. 1994). Defects in GALC are the cause of leukodystrophy globoid cell (GLD) (MIM:245200), also called Krabbe disease (Wenger et al. 1997). Pubmed7852280 Pubmed9338580 Reactome Database ID Release 431606564 Reactome, http://www.reactome.org ReactomeREACT_115737 Reviewed: Stephan, R, 2011-10-31