Binding of NS1 to poly(A)-binding protein II (PABII) GENE ONTOLOGYGO:0046778 Pubmed10205180 Reactome Database ID Release 43168883 Reactome, http://www.reactome.org ReactomeREACT_6287 The influenza virus non-structural protein 1 (NS1) binds to the host cell's poly(A)-binding protein II (PABII) thus preventing PABII from properly extending the poly-A tail of pre-mRNA within the host cell nucleus. These pre-mRNAs are then prevented from exiting the nucleus. NS1 Homodimer NS1:PAB II Complex