Activation of PP2A by Xylulose-5-phosphate Authored: Gopinathrao, G, 2005-05-14 18:58:58 Pubmed12110366 Pubmed12684532 Pubmed12721358 Reactome Database ID Release 43163769 Reactome, http://www.reactome.org ReactomeREACT_2177 Xylulose-5-phosphate binds to Protein phosphatase 2A (PP2A), activating it. This regulatory step may be the crucial physiological link explaining the coordinately increased rates of glycolysis and lipogenesis generally observed in individuals consuming high-carbohydrate diets. PP2A-ABdeltaC complex Inactive PP2A-ABdeltaC complex