PS is decarboxylated to PE by PISD At the inner mitochondrial (IM) membrane, phosphatidylserine decarboxylase proenzyme (heterodimer of two chains from the same protein) (PISD) decarboxylates phosphatidylserine (PS) to phosphatidylethanolamine (PE). This event has been inferred from rats and limited data for a human PISD (Forbes et al. 2007). Authored: Williams, MG, 2011-09-14 EC Number: 4.1.1.65 Edited: Williams, MG, 2011-08-12 Pubmed17478478 Reactome Database ID Release 431483212 Reactome, http://www.reactome.org ReactomeREACT_121085