PC is transphosphatidylated to PG by PLD1-4/6 Authored: Williams, MG, 2011-09-14 EC Number: 3.1.4.4 Edited: Williams, MG, 2011-08-12 In the endoplasmic reticulum (ER) membrane, phospholipase D1-4,6 (PLD1-4,6) transphosphatidylates phosphatidylcholine (PC) with glycerol to displace choline (Cho) and form phosphatidylglycerol (PG). This reaction is inferred from rats, but PLD enzymes are present in humans (Hammond et al. 1995, Steed et al. 1998, Cao et al. 1997). Pubmed8530346 Pubmed9140189 Pubmed9761774 Reactome Database ID Release 431483142 Reactome, http://www.reactome.org ReactomeREACT_121402