PA is converted to CDP-DAG by CDS1 At the endoplasmic reticulum (ER) membrane, phosphatidate cytidylyltransferase 1 (CDS1) converts phosphatidic acid (PA) and cytidine triphosphate (CTP) into cytidine diphosphate-diacylglycerol (CDP-DAG). Both ER and mitochondrial membranes have the capability to synthesize cytidine diphosphate-diacylglycerol (CDP-DAG) with phosphatidate cytidylyltransferase 1 and 2 (CDS1 and CDS2) (Lykidis et al. 1997). However, transport of CDP-DAG between organelles cannot be ruled out (Stuhne-Sekalec et al. 1986). Authored: Williams, MG, 2011-09-14 EC Number: 2.7.7.41 Edited: Williams, MG, 2011-08-12 Pubmed3718705 Pubmed9407135 Reactome Database ID Release 431483121 Reactome, http://www.reactome.org ReactomeREACT_121066