PI3P is dephosphorylated to PI by MTM[3] at the late endosome membrane At the late endosome membrane, myotubularin (MTM1), myotubularin-related protein 2 (MTMR2), myotubularin-related protein 4 (MTMR4), and myotubularin-related protein 7 (MTMR7) dephosphorylate phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol (PI).<br><br>The following lists the above proteins with their corresponding literature references: MTM1 (Cao et al. 2007, Cao et al. 2008, Tsujita et al. 2004, Tronchere et al. 2004, Kim et al. 2002); MTMR2 (Cao et al. 2008, Kim et al. 2002); MTMR4 (Lorenzo et al. 2006); and MTMR7 (Mochizuki & Majerus 2003, Lorenzo et al. 2006). Authored: Williams, MG, 2011-10-18 EC Number: 3.1.3.64 Edited: Williams, MG, 2011-08-12 Pubmed11733541 Pubmed12890864 Pubmed14660569 Pubmed14722070 Pubmed16787938 Pubmed17651088 Pubmed18524850 Reactome Database ID Release 431675795 Reactome, http://www.reactome.org ReactomeREACT_120958 Reviewed: Wakelam, Michael, 2012-05-14