Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA Authored: Garapati, P V, 2012-01-11 EC Number: 1.3.3.6 Edited: Garapati, P V, 2012-01-11 Pubmed11500517 Pubmed11734571 Pubmed8656081 Reactome Database ID Release 432066787 Reactome, http://www.reactome.org ReactomeREACT_120938 Retroconversion of C24:6(n-3) to docosahexaenoic acid (22:6(n-3) involves the initial oxidation of tetracosahexaenoyl-CoA to an intermediate 1-(2E,6Z,9Z,12Z,15Z,18Z,21Z-tetracosaheptaenoyl)-CoA (delta2-THA-CoA). This step is catalysed by the peroxisomal enzyme Straight-chain acyl-CoA oxidase (SCOX) (Ferdinandusse et al. 2001).