SREBP1A/2 Binds the LSS Promoter Authored: May, B, 2012-07-26 Edited: May, B, 2012-07-26 Pubmed18559965 Pubmed9748295 Reactome Database ID Release 432426154 Reactome, http://www.reactome.org ReactomeREACT_147766 Reviewed: Liang, Guosheng, 2012-08-25 SREBF1A/2 Binds the LSS Promoter SREBP1A (SREBF1A) or SREBP2 binds and transactivates the promoter of the LSS gene (Pai et al. 1998, Rome et al. 2008). SREBP1A and SREBP2 activate LSS equally (Pai et al. 1998). SREBP1A/2 Dimer SREBP1A/2:LSS gene LSS gene