SREBP1A/2 Binds the CYP51A1 Promoter Authored: May, B, 2012-07-26 Edited: May, B, 2012-07-26 Pubmed18559965 Pubmed18654640 Pubmed9748295 Reactome Database ID Release 432426163 Reactome, http://www.reactome.org ReactomeREACT_147786 Reviewed: Liang, Guosheng, 2012-08-25 SREBF1A/2 Binds the CYP51A1 Promoter SREBP1A (SREBF1A) or SREBP2, together with NF-Y and SP1, bind and transactivate the promoter of the CYP51A1 gene (Pai et al. 1998, Reed et al. 2008, Rome et al. 2008). SREBP1A and SREBP2 activate CYP51A1 equally (Pai et al. 1998). NF-Y SREBP1A/2 Dimer SREBP1A/2:NF-Y:SP1:CYP51A1 gene CYP51A1 gene