p-STAT1 dimer bound to p-IFNGR1 p-STAT1(Y701) bound to p-IFNGR1 Phosphorylation of STAT1 at Ser727 Authored: Garapati, P V, 2010-06-08 EC Number: 2.7.11 Edited: Garapati, P V, 2010-07-07 Kinases like Protein kinase C delta (PKC-delta) and Calcium/calmodulin-dependent protein kinase II (CaMK II ) can phosphorylate STAT1 at serine 727 (S727). This phosphorylation is not required for STAT1 homodimer formation, nuclear translocation and DNA binding. However, it is essential for the full transcriptional activation of STAT1. Pubmed11972023 Pubmed15322115 Reactome Database ID Release 43909552 Reactome, http://www.reactome.org ReactomeREACT_25369 Reviewed: Abdul-Sater, AA, Schindler, C, 2010-08-17 has a Stoichiometric coefficient of 2