Caspase-9 binds DCC:DIP13alpha complex Authored: Garapati, P V, 2008-07-16 14:42:16 Edited: Garapati, P V, 2008-07-30 10:24:23 Pubmed11248093 Pubmed12011067 Reactome Database ID Release 43373700 Reactome, http://www.reactome.org ReactomeREACT_22246 Reviewed: Cooper, HM, 2010-02-16 The ADD domain of DCC complexed with DIP13alpha interacts with the initiator caspase-9, leading to caspase activation and caspase-dependent cell death. DIP13alpha appears to function as a required adaptor to mediate DCC-caspase-9 interaction. DCC:DIP13alpha:Caspase-9 DCC:DIP13alpha Cleaved Caspase-9