Interleukin-1 family are secreted Authored: Ray, KP, 2010-05-17 Edited: Jupe, S, 2010-08-06 IL-1 Beta lacks signal sequences for compartmentation within the Golgi and classical secretory vesicles, so release of the mature form to extracellular compartments requires nonclassical mechanisms of secretion which are poorly understood. Three models with distinct mechanisms have been proposed to date (see Qu et al. 2007). Pubmed17641058 Reactome Database ID Release 43449058 Reactome, http://www.reactome.org ReactomeREACT_23994 Reviewed: Pinteaux, E, 2010-09-06 Interleukin-1 family Interleukin-1 family