tBID binds to inactive BAK protein Pubmed10950869 Reactome Database ID Release 43168848 Reactome, http://www.reactome.org ReactomeREACT_6153 tBID binds to its mitochondrial partner BAK to release cytochrome c. It has been observed in mouse systems that the activated tBID results in an allosteric activation of BAK. Activated BAX induces intramembranous oligomerization leading to a pore for cytochrome c efflux. tBID bound to inactive BAK human protein covalent binding