DFF40 homodimer/homooligomer Association of DFF40 with chromatin Authored: Matthews, L, 2008-01-29 12:03:24 Direct interactions between the histone H1 C-terminal domain and DFF40/CAD possibly target the nuclease to chromatin linker DNA promoting the linker DNA cleavage during the terminal stages of apoptosis (Widlak et al., 2005). Noteworthy, it has been reported that DFF40/DFF45 complexes could also associate with chromatin and be activated with caspase-3 in DNA-bound state (Korn et al., 2005). Edited: Matthews, L, 2008-01-29 12:04:16 Edited: Matthews, L, 2008-05-02 11:31:29 Pubmed10318789 Pubmed15572351 Pubmed15910001 Reactome Database ID Release 43211239 Reactome, http://www.reactome.org ReactomeREACT_13514 Reviewed: Widlak, P, 2008-05-07 23:54:18 Histone H1 bound chromatin DNA DFF40 associated with chromatin