FAS Mediated Activation of Pro-caspase 8 At the beginning of this reaction, 1 molecule of 'FASL:FAS Receptor Trimer:FADD:pro-Caspase-8 DISC' is present. At the end of this reaction, 1 molecule of 'p10 subunit of Caspase 8', 1 molecule of 'p18 subunit of Caspase 8', and 1 molecule of 'FASL:FAS Receptor Trimer:FADD complex' are present.<br><br> This reaction takes place in the 'cell'.<br> Pubmed9721089 Reactome Database ID Release 4373945 Reactome, http://www.reactome.org ReactomeREACT_279 FASL:FAS Receptor Trimer:FADD:pro-Caspase-8 DISC FASL:FAS Receptor Trimer:FADD complex