IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 STAT1 Phosphorylation of STAT1 Authored: Garapati, P V, 2010-07-07 EC Number: 2.7.10 Edited: Garapati, P V, 2010-07-07 Phosphotyrosine on STAT2 acts as docking site for STAT1 molecules. STAT1 binds to phosphorylated STAT2 and this is followed by STAT1 phosphorylation on tyrosine residue 701 (Y701) and is followed by p-STAT2:p-STAT1 heterodimer formation and nuclear translocation. Pubmed10982844 Pubmed8232552 Reactome Database ID Release 43909726 Reactome, http://www.reactome.org ReactomeREACT_25017 Reviewed: Abdul-Sater, AA, Schindler, C, 2010-08-17