Smad7:SMURF1 Smad7:SMURF1 complex translocates to the cytosol Authored: Orlic-Milacic, M, 2012-04-04 Edited: Jassal, B, 2012-04-10 Pubmed12519765 Reactome Database ID Release 432169016 Reactome, http://www.reactome.org ReactomeREACT_121294 Reviewed: Huang, Tao, 2012-05-14 XPO1 (CRM1) bound to Smad7:SMURF1 complex enables translocation of Smad1:SMURF1 to the cytosol. In this study, recombinant human SMURF1, recombinant mouse Smad7 and recombinant XPO1 (species not specified, assumed to be human) were exogenously expressed in COS7 cells (Tajima et al. 2003). Smad7:SMURF1:XPO1