Defective GALNS does not hydrolyse sulfate from Gal6S Authored: Jassal, B, 2012-05-21 Defective GALNS does not hydrolyse sulfate from galactose 6-sulfate in KS Edited: Jassal, B, 2012-05-21 From a recent review of mutations for MPSIVA (MIM:253000) (Tomatsu et al. 2005), almost 80% of mutations in N-acetylgalactosamine 6-sulfatase (GALNS; MIM:612222) were missense mutations and of these, the most common ones are R386C, G301C and I113F. Pubmed16287098 Reactome Database ID Release 432263490 Reactome, http://www.reactome.org ReactomeREACT_147848 Reviewed: Alves, Sandra, 2012-08-27 Reviewed: Coutinho, Maria, 2012-08-27