dsDNA:AIM2 AIM2 binds dsDNA AIM2 binds to cytosolic dsDNA via its C-terminal HIN domain. The source of the dsDNA can be can be viral, bacterial or derived from the host (Hornung et al. 2009, Muruve et al. 2008). Multiple AIM2 molecules may bind the same dsDNA (Fernandes-Alnemri et al. 2008). Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Pubmed18288107 Pubmed19158675 Pubmed19158676 Pubmed19158679 Reactome Database ID Release 43844619 Reactome, http://www.reactome.org ReactomeREACT_75821 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06 Reviewed: Wong, Edmond, 2011-06-06