P2X7 mediates loss of intracellular K+ Authored: Jupe, S, 2010-04-22 Edited: Jupe, S, 2011-04-28 Low level or transient activation of P2X7 leads to reversible opening of a membrane channel permeable to small cations such as Na+, Ca2+ and K+ (Adinolfi et al. 2005). Pubmed11157473 Pubmed18404507 Pubmed9023774 Reactome Database ID Release 43877187 Reactome, http://www.reactome.org ReactomeREACT_75889 Reviewed: Kufer, TA, 2011-04-28 Reviewed: Rittinger, K, 2011-06-06 Reviewed: Wong, Edmond, 2011-06-06