C4-binding protein:C4b C4 binding protein:C4bC2a C4b binding protein displaces C2a Authored: Jupe, S, 2010-10-26 C4 binding protein accelerates the decay of C4bC2a in a dose-dependent fashion. The mechanism of this is poorly understood, but is distinct from Factor I mediated degradation of C4b and believed to represent the displacement of C2a from specific binding sites on C4b (Gigli et al. 1979). Edited: Jupe, S, 2010-11-01 Pubmed293746 Reactome Database ID Release 43981680 Reactome, http://www.reactome.org ReactomeREACT_118738 Reviewed: Bradley, DT, 2012-02-13 Reviewed: Fraczek, LA, 2012-02-13 has a Stoichiometric coefficient of 7