Capping complex (with freed 5'- GMP) RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA mRNA capping factors phospho-Spt5 Methylation of GMP-cap by RNA Methyltransferase Authored: Buratowski, S, 2003-10-15 15:18:41 EC Number: 2.1.1.56 In the final step of the capping reaction, the methyltransferase takes a methyl group from S-adenosyl-methionine to the N7 position of the cap guanine. N7G-methyltransferase (MT) mediated reaction can be represented as:<BR>GpppN(pN)n + S-adenosylmethionine (Adomet) ->m7GpppN(pN)n + S-adenosylhomocysteine (Adohcy).<P> Pubmed9790902 Reactome Database ID Release 4377090 Reactome, http://www.reactome.org ReactomeREACT_404 TFIIH