TRAF6:p-IRAK2 p-IRAK2:oligo-TRAF6 IRAK2 induces TRAF6 oligomerization Authored: Shamovsky, V, 2010-06-01 Edited: Shamovsky, V, 2012-11-06 Pubmed17878161 Reactome Database ID Release 43936963 Reactome, http://www.reactome.org ReactomeREACT_25119 Reviewed: Gillespie, ME, 2010-11-30 Reviewed: Napetschnig, Johanna, 2012-11-16 The mechanism by which IRAK-2 induces TRAF6 E3 ligase activity remains to be deciphered, but one possibility is that IRAK-2 may direct TRAF6 oligomerization. has a Stoichiometric coefficient of 2