Serum amyloid P-component forms homopentamers Authored: Jupe, S, 2010-10-15 Edited: Jupe, S, 2011-04-08 Pubmed8114934 Reactome Database ID Release 43976723 Reactome, http://www.reactome.org ReactomeREACT_75902 Reviewed: Perry, G, 2011-04-08 Serum amyloid P component (SAP) is a member of the pentraxin family, characterized by the formation of pentameric ring structures. Each member of the ring has two associated calcium ions. SAP is an acute phase reactant, highly induced by IL-6. It has 50% homology with the related C-reactive peptide. has a Stoichiometric coefficient of 10 has a Stoichiometric coefficient of 5 Serum amyloid P-component homopentamer