Benzoquinoid ansamycins HSP90 is inactivated by binding to benzaquinoid ansamycins Authored: Orlic-Milacic, M, 2011-11-04 Benzoquinoid ansamycins (geldanamycin, herbimycin, and geldanamycin derivatives 17-AAG, 17-DMAG and IPI-504) are antitumor antibiotics that inactivate HSP90 by binding to its substrate-binding pocket. Edited: D'Eustachio, P, 2011-11-07 Edited: Jassal, B, 2011-11-07 Edited: Matthews, L, 2011-11-07 Edited: Wu, G, 2011-11-07 Pubmed9108479 Reactome Database ID Release 431218824 Reactome, http://www.reactome.org ReactomeREACT_115865 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15 has a Stoichiometric coefficient of 2 HSP90 HSP90:Benzoquinoid ansamycins