ABCA1-mediated transport of intracellular phospholipid to the cell surface Authored: D'Eustachio, P, 2008-05-12 17:46:52 Edited: D'Eustachio, P, 2008-06-13 14:03:50 In an ATP-dependent reaction, ATPA1 mediates the movement of intracellular phospholipid to the extracellular face of the plasma membrane. Cholesterol associated with cytosolic vesicles is a substrate for this reaction. Under physiologocal conditions, the active form of ABCA1 is predominantly a tetramer associated with apoA-I lipoprotein (Denis et al. 2004; Vedhachalam et al., 2007). The number of lipid molecules transported per ATP consumed is not known. Pubmed15280376 Pubmed17604270 Reactome Database ID Release 43216757 Reactome, http://www.reactome.org ReactomeREACT_13627 Reviewed: Jassal, B, 2008-06-13 14:05:49