Trimethylation of Histone H3 by PRDM9 As inferred from experiments in vitro with mouse Prdm9, human PRDM9 methylates histone H3 dimethylated at lysine-4 to yield histone H3 trimethylated at lysine-4. Authored: May, B, 2011-02-07 Edited: May, B, 2011-02-07 Pubmed16292313 Reactome Database ID Release 431214188 Reactome, http://www.reactome.org ReactomeREACT_27242 Reviewed: Bolcun-Filas, E, 2011-02-25 Reviewed: Cohen, PE, 2011-02-04 Reviewed: Holloway, JK, 2011-02-04 Reviewed: Lyndaker, A, 2011-02-25 Reviewed: Schimenti, JC, 2011-02-04 Reviewed: Strong, E, 2011-02-25 has a Stoichiometric coefficient of 2 Nucleosome with Histone H3 Dimethylated at Lysine-4 Nucleosome with Histone H3 Trimethylated at Lysine-4