Heterdimerization of CEACAMs Authored: Ouwehand, W.H., 2007-11-12 16:45:54 Pubmed17167768 Reactome Database ID Release 43202717 Reactome, http://www.reactome.org ReactomeREACT_12073 Reviewed: Zwaginga, JJ, 2007-11-12 16:47:00 The presence of CEACAM dimers was shown to lead to an increase in the binding of the integrin alph5 beta1 receptor to its ligand fibronectin, without changing its cell surface levels, resulting in increased adhesion of these cells to fibronectin. has a Stoichiometric coefficient of 2 Neutrophil CEACAMs affecting integrin binding to fibronectin CEACAM heterodimer