vitamins transported by SMVT vitamins transported by SMVT Na+-dependent multivitamin transporter Authored: Jassal, B, 2009-07-17 Biotin (vitamin H or B7) is a water-soluble B-complex vitamin. Biotin is a cofactor in the metabolism of fatty acids and leucine, and it plays a role in gluconeogenesis. D-Pantothoate (vitamin B5), is a water-soluble vitamin needed to form coenzyme-A (CoA), and is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. Lipoic acid is an organosulfur compound, the R-enantiomer of which is an essential cofactor for many enzyme complexes.<br><br>The human SLC5A6 encodes the Na+-dependent multivitamin transporter SMVT (Prasad PD et al, 1999; Wang H et al, 1999). SMVT co-transports these vitamins/cofactors into cells with Na+ ions electrogenically. Edited: Jassal, B, 2009-07-17 Pubmed10329687 Pubmed10334869 Reactome Database ID Release 43429581 Reactome, http://www.reactome.org ReactomeREACT_22320 Reviewed: He, L, 2009-08-24 has a Stoichiometric coefficient of 2