Anions transported by Aquaporin-6 Anions transported by Aquaporin-6 Passive Transport of Anions out of Vesicles by Aquaporin-6 Aquaporin-6 (AQP6) passively transports anions across membranes. Rat AQP6 has been shown to transport anions, with the highest permeability for nitrate, the lowest permeability for fluoride, and low permeability for water. In rat AQP6 is expressed in the acid-secreting type-A intercalated cells of renal ducts where it co-localizes with the proton-ATPase in the membranes of intracellular vesicles. AQP6 is gated by low pH. Authored: May, B, 2009-08-06 Edited: May, B, 2009-08-06 Pubmed8812490 Reactome Database ID Release 43432036 Reactome, http://www.reactome.org ReactomeREACT_23883 Reviewed: Beitz, E, 2010-06-24 Reviewed: Calamita, G, 2010-07-15 Reviewed: Mathai, JC, MacIver, B, 2010-07-31