SLCO2B1 substrates SLCO2B1 substrates SLCO2B1 has a narrow substrate specificity Authored: Jassal, B, 2010-06-18 Edited: Jassal, B, 2010-06-18 Pubmed11159893 Reactome Database ID Release 43879562 Reactome, http://www.reactome.org ReactomeREACT_23829 Reviewed: He, L, 2010-07-07 SLCO2B1 (formerly OATP-B) is abundantly expressed in human liver, where it is localized at the basolateral membrane of hepatocytes. It has a narrow substrate range, able to transport bromosulphophthalein (BSP), estrone-3-sulphate and dehydroepiandrosterone-sulphate (DHEAS) (Kullak-Ublick GA et al, 2001).