ligands of SLC29A4 ligands of SLC29A4 Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 Authored: Jassal, B, 2010-05-12 Edited: Jassal, B, 2010-05-12 Pubmed15448143 Pubmed16873718 Reactome Database ID Release 43727768 Reactome, http://www.reactome.org ReactomeREACT_22188 Reviewed: He, L, 2010-05-10 The human gene SLC29A4 encodes the equilibrative nucleoside transporter 4 (ENT4). It is ubiquitously expressed and mediates the reversible transport of the nucleoside adenosine at acidic pH (this transport is absent at pH 7.4) (Barnes K et al, 2006). ENT4 has also been shown to mediate the transport of biogenic amines such as serotonin, dopamine, norepinephrine and epinephrine. For this reason, ENT4 is also known as the plasma membrane monoamine transporter (PMAT) (Engel K et al, 2004).