ligands of SLC29A3 ligands of SLC29A3 Equilibrative transport (import) of nucleosides and adenine by solute carrier family 29 (nucleoside transporters), member 3 Authored: Jassal, B, 2010-05-12 Edited: Jassal, B, 2010-05-12 Pubmed15701636 Reactome Database ID Release 43727767 Reactome, http://www.reactome.org ReactomeREACT_22395 Reviewed: He, L, 2010-05-10 The human gene SLC29A3 encodes the equilibrative nucleoside transporter 3 (ENT3). It is abundant in many tissues, especially the placenta and is localized intracellularly on the lysosomal membrane. ENT3 mediates the reversible transport of nucleosides and the nucleobase adenine (Baldwin SA et al, 2005). Defects in SLC29A3 are the cause of H syndrome, an autosomal recessive disorder(Molho-Pessach V et al, 2008).