Group 3 - Selective Cl- transport Authored: Jassal, B, 2009-06-23 Edited: Jassal, B, 2009-06-23 Group 3 members (SLC26A7 and 9) function as ion channels. SLC26A7 encodes an ion channel which is abundantly expressed in medullary collecting duct cells of the kidney, high endothelial venule enothelial cells (HEVEC) and gastric parietal cells (Vincourt JB et al, 2002; Lohi H et al, 2002). SLC26A9 encodes an ion channel which is predominantly expressed on the lumenal side of the bronchiolar and alveolar epithelium of lung (Lohi H et al, 2002). Both these ion channels appear to transport Cl- without cotransport of HCO3- (Kim KH et al, 2005; Dorwart MR et al, 2007). Pubmed11829495 Pubmed11834742 Pubmed15591059 Pubmed17673510 Reactome Database ID Release 43427570 Reactome, http://www.reactome.org ReactomeREACT_19248 Reviewed: He, L, 2009-08-24