RhBG mediates ammonium influx into kidney collecting duct cells Authored: Jassal, B, 2009-11-12 Edited: Jassal, B, 2009-11-12 Pubmed11024028 Pubmed15284342 Reactome Database ID Release 43446278 Reactome, http://www.reactome.org ReactomeREACT_20571 Reviewed: He, L, 2009-11-12 The human gene RhBG encodes a Rhesus blood group family type B glycoprotein which is expressed mainly in the kidney but is also found in the liver. The liver and kidney are important tissues for ammonium metabolism and excretion. RhBG is located on the basolateral membrane and mediates the reversible transport of ammonium in and out of renal collecting duct cells in an electroneutral manner, with H+ transported the other way (Ludewig U, 2004; Liu Z et al, 2001).