Association of PARVA with TESK1 Authored: Matthews, L, 2009-10-12 Edited: Matthews, L, 2009-11-12 Pubmed11555644 Pubmed12027893 Pubmed15584898 Pubmed15817463 Reactome Database ID Release 43446372 Reactome, http://www.reactome.org ReactomeREACT_20609 Reviewed: Wu, C, 2009-11-12 The association of PARVA with TESK1 appears to suppress cell spreading (Lalonde et al. 2005). TESK1 can phosphorylate cofilin and promote F-actin polymerization and cell spreading (Tsumura et al., 2005 ; Toshima et al., 2001; Leeksma et al., 2002). PARVA associates with testicular protein kinase 1 (TESK1) and inhibits its activity (Lalonde et al. 2005). PARVA:TESK1