Formation of Axial/Lateral Elements of Synaptonemal Complex Authored: May, B, 2010-07-19 Axial elements begin assembling as short linear segments along the long axis of the chromosome in leptotene phase. Eventually the short segments will fuse to form the complete axial element along the entire length of the chromosome. After synapsis the axial elements are also known as lateral elements of the synaptonemal complex. Within axial elements the sister chromatids are bound together by meiotic cohesin (Prieto et al. 2004, Garcia-Cruz et al. 2010). The bound chromatids are anchored to a complex containing SYCP2 and SYCP3 via a direct or indirect interaction with cohesin (Garcia-Cruz et al. 2010). Edited: May, B, 2010-07-19 Pubmed15125634 Pubmed20634189 Reactome Database ID Release 43912389 Reactome, http://www.reactome.org ReactomeREACT_75874 Reviewed: Bolcun-Filas, E, 2011-02-25 Reviewed: Cohen, PE, 2011-02-04 Reviewed: Holloway, JK, 2011-02-04 Reviewed: Lyndaker, A, 2011-02-25 Reviewed: Schimenti, JC, 2011-02-04 Reviewed: Strong, E, 2011-02-25 Axial/Lateral Element of Synaptonemal Complex Meiotic Cohesin Complex